Evaluation of Selenium and Vitamin E Levels in Women with Recurrent Miscarriage

Authors

  • Zeina J. AbduLshaheed
  • Ali A. H. Albakaa
  • Hasan Abd Ali Khudhair

DOI:

https://doi.org/10.32792/utq/utjsci/v10i1(SI).972

Keywords:

Recurrent miscarriage, Selenium, Vitamin E, Pregnancy

Abstract

The most frequent pregnancy issue is a miscarriage, which is defined as the spontaneous end of pregnancy before the fetus reaches viability. The current research aims to identify the potential significance of selenium (Se) and vitamin E (VE) as predictive diagnostic biomarkers in recurrent pregnancy loss (RPL).

Methods: A case control study that included three study groups; 35 women with RPL, 30 non-aborted pregnant (NAP) women, and 25  healthy women. After rigorously applying the eligibility requirements, patients were chosen from those visiting Bint Al-Huda Teaching Hospital and Suq Al-Shuyukh General Hospital in Thi-Qar Province (Iraq). Serum VE and serum Se levels were determined using the ELISA and atomic absorption spectrophotometer techniques, respectively.

 Results: The outcomes showed that the RPL group's serum VE and Se below normal levels were (88.6% and 62.9% respectively) lower than in the healthy control group (28% and 24% respectively). The level of VE was depleted in NAP group (93.3%) compared to HC group (28%) with significant differences, whereas the level of Se was significantly lower in RPL group (62.9%) compared NAP group (13.3%).

Conclusions: A significant positive association of VE and Se in RPL and a significant negative association of VE and Se in NAP and HC. 

 

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Published

2023-04-29

How to Cite

Evaluation of Selenium and Vitamin E Levels in Women with Recurrent Miscarriage. (2023). University of Thi-Qar Journal of Science, 10(1(SI), 77-83. https://doi.org/10.32792/utq/utjsci/v10i1(SI).972