Association between inflammatory cytokines and other Biochemical parameters in patients after 48 hrs of first myocardial infarction (MI)

Abstract

Myocardial infarction (MI) is a term used to describe a heart attack that occurs when blood flow to the heart muscle reduced, and plaque builds up in the lining of the coronary arteries, resulting in insufficient oxygen supply. The study was conducted on a number of participants, including 100 cases and 70 controls, who were matched for gender and age. The blood indicators in question were examined using standard laboratory techniques and equipment. The study aimed to study the relationship between inflammatory cytokines, lipid profiles, and transaminase enzyme in patients 48 hours after myocardial infarction. The results indicated that there are differences between cases and controls for inflammatory cytokines (IL-8, IL-12, and IFN-??). Moreover, total cholesterol (TC), low-density lipoprotein (LDL), and high-density lipoprotein (HDL) were decreased in cases in comparison with controls, while triglyceride (TG) was high in patients after MI. However, patients' aspartate transaminase (AST) levels were meaningfully higher than in controls.