Histopathological Changes of Two Antigens Prepared from Methicillin-Resistant Staphylococcus aureus in Rats

Authors

  • Zainab Dakhil Degaim
  • Wafaa Sadoon Shani
  • Saad Salman Hamim

Keywords:

MRSA, Hla, HIBS, spleen, thymus, histopathology changes

Abstract

The aim of the present study was to determine the effect of two prepared antigens fromMethicillin-resistantStaphylococcus aureus (MRSA), whichincluded crude alpha toxin (Hla) and heat inactivate bacterial suspension (HIBS)  in rats through the examination of the inflammatory response of both antigens on primary and secondary lymphoid organs (thymus gland and spleen), respectively. Examination of sections from spleen of rats treated with HIBS antigen induced high immune response compared with rats treated with Hla antigen which induce mild immune response by established changes. The histological observations on sections from thymus gland of rats treated with HIBS had the ability to induce different changes than Hla antigen compared with control group.

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Published

2020-12-05

Issue

Vol. 7 No. 2 (2020): Special Issue (The 4TH Scientific Conference)

Section

Articles

How to Cite

Histopathological Changes of Two Antigens Prepared from Methicillin-Resistant Staphylococcus aureus in Rats. (2020). University of Thi-Qar Journal of Science, 7(2), 54-59. https://jsci.utq.edu.iq/index.php/main/article/view/712