Effects of Metformin and diet on hemoglobin, cholesterol and triglyceride levels of Type 2 diabetic Patients

Abstract

Metformin is recommend as the first line oral agent to be used patients with non-insulin-dependent diabetes mellitus(Type 2 Diabetic).The study was prospectively performed in diabetic and endocrine center of Nassiriyah city .The present study aimed to shed light on metformin  and  hemoglobin(Hb) and lipid profile in type II diabetic patients with diet and without diet . Our study included 60  patients treated with metformin  for Twelve-week . The subjects were divided into three groups. Group I as control, group II  patients received Metformin- (1000/2 mg/day) with diet and  group III  patients received the Metformin-(1000/2 mg/day) without diet  all these patient had been selected from those patients visit . The Hb concentration and lipid profile were been examine after 3 months of treatment.In present study we found the hemoglobin concentration reduced in group II with diet patient compare with the group III and control group also reduced in the group III without diet patient compare with control group, as same time This study showed that the treatment with metformine  led to, reductions observed in the cholesterol concentrations of the group II diabetic patients with diet compared with the group III administered MET respective without  diet  diabetic and compared with control, Also we found the triglyceride concentrations of diabetic patients in group administered MET respective with diet were significantly (p<0.05) reduced compared with that of without diet  diabetic and  control therefore it was considered predisposing factor to reduced damage diabetes. For this reason; continuous taking of metaformin should be important.