Identify The Urinary Bladder Cancer Patterns In Nasiriyah city / Thi-Qar Province – Iraq
DOI:
https://doi.org/10.32792/utq/utjsci/v10i2.1091Keywords:
Bladder cancer, Carcinomas, NasiriyahAbstract
This study aims to shed light on the generality types of urinary bladder cancer in the city of Nasiriyah / Thi-Qar Province – Iraq. The study includes cases that were registered in the Department of Pathology in Al-Hussein Teaching Hospital and Private Laboratories. Patient records were analyzed for information regarding age, sex, residence, and cancer type. A total of 114 sufferers of bladder cancer were obtained. The data taking period was from January 1, 2021 to April 30, 2022. Tumors were diagnosed mainly in the private laboratories of two consultant pathologists in Nasiriyah. The results showed 107 (93.86%) transitional cell carcinomas with a mean age of 47 years, in addition to 6 (5.26%) squamous cell carcinomas with a mean age of 69 years and 1 adenocarcinoma (0.88%) at the age of 51 years. Out of all cancer cases, males accounted for 74.56% whilst females accounted for 25.44%, indicating a male to female ratio of 4:1. Additionally, males showed a clear dominance in the totality of the histological grades. The age range with the highest number of cancer cases was between 70-79 years old (n = 37; 32.45%), while the age range with the lowest number of cases was between 23-39 years old (n = 3; 2.63%). The current study concluded that the majority types of bladder cancer in the city of Nasiriyah / Thi-Qar Province - Iraq are transitional cell carcinomas with an average age of 47 years. Among all cancers, males had the highest incidence.
Received: 2023-07-19
Revised: 2023-08-11
Accepted: 2023-09-30
References
W. Pradidarcheep, C. Wallner, N. F. Dabhoiwala, and W. H. Lamers, Anatomy and histology of the lower urinary tract, vol. 202. 2011. doi: 10.1007/978-3-642-16499-6_7.
H. Zhou, C. C. Guo, and J. Y. Ro, Urinary Bladder Pathology. 2021. doi: 10.1007/978-3-030-71509-0.
S. Fayez and E. L. Meski, “MULTI-TARGET DIRECTED LIGANDS (MTDLS) AS POTENTIAL THERAPIES FOR BLADDER CANCER,” USA/beirut, 2021.
N. A. Lakkis, S. M. Adib, G. N. Hamadeh, R. T. El-Jarrah, and M. H. Osman, “Bladder Cancer in Lebanon: Incidence and Comparison to Regional and Western Countries,” Cancer Control, vol. 25, no. 1, pp. 1–7, 2018, doi: 10.1177/1073274818789359.
R. Lee and M. J. Droller, “the Natural History of Bladder Cancer,” Urol. Clin. North Am., vol. 27, no. 1, pp. 1–13, 2000, doi: 10.1016/s0094-0143(05)70229-9.
V. Bilim, H. Kuroki, Y. Shirono, M. Murata, K. Hiruma, and Y. Tomita, “Advanced Bladder Cancer: Changing the Treatment Landscape,” J. Pers. Med., vol. 12, no. 10, 2022, doi: 10.3390/jpm12101745.
M. Burger et al., “Epidemiology and risk factors of urothelial bladder cancer,” Eur. Urol., vol. 63, no. 2, pp. 234–241, 2013, doi: 10.1016/j.eururo.2012.07.033.
S. S. Mukrimaa et al., “Associations between Bladder Cancer Risk Factors and Tumor Stage and Grade at Diagnosis,” J. Penelit. Pendidik. Guru Sekol. Dasar, vol. 6, no. August, p. 128, 2016.
H. Tang et al., “Pioglitazone and bladder cancer risk: a systematic review and meta-analysis,” Cancer Med., vol. 7, no. 4, pp. 1070–1080, 2018, doi: 10.1002/cam4.1354.
M. Mazonakis, E. Lyraraki, M. Tolia, and J. Damilakis, “Risk for second bladder and rectal malignancies from cervical cancer irradiation,” J. Appl. Clin. Med. Phys., vol. 22, no. 7, pp. 103–109, 2021, doi: 10.1002/acm2.13274.
H. Zhang, A. Yu, A. Baran, and E. Messing, “Risk of second cancer among young prostate cancer survivors,” Radiat. Oncol. J., vol. 39, no. 2, pp. 91–98, 2021, doi: 10.3857/roj.2020.00857.
X. Huang et al., “The inflammatory microenvironment and the urinary microbiome in the initiation and progression of bladder cancer,” Genes Dis., vol. 8, no. 6, pp. 781–797, 2021, doi: 10.1016/j.gendis.2020.10.002.
A. S. Al-Samawi and S. M. Aulaqi, “Urinary
bladder cancer in Yemen,” Oman Med. J., vol. 28, no. 5, pp. 337–340, 2013, doi: 10.5001/omj.2013.977.
H. Ragab, M. El-Badry, M. Abdel Ghani, and M. Aboelhassan, “Urinary Bladder Carcinoma Pattern at Urology Minia University Hospital,” Minia J. Med. Res., vol. 32, no. 1, pp. 36–43, 2021, doi: 10.21608/mjmr.2022.220576.
S. Vaidya, M. Lakhey, K. C. Sabira, and S. Hirachand, “Rothelial tumours of the urinary bladder: A histopathological study of cystoscopic biopsies,” J. Nepal Med. Assoc., vol. 52, no. 191, pp. 475–478, 2013, doi: 10.31729/jnma.2053.
M. Mubarak, J. I. Kazi, A. Hashmi, M. Hussain, S. A. Naqvi, and S. A. H. Rizvi, “Urinary Bladder Tumors in Southern Pakistan: A Histopathological Perspective Muhammed,” Middle East J. Cancer 2014;, vol. 3, no. 5, pp. 167–73, 2014.
M. Ploeg, K. K. Aben, C. A. Hulsbergen-van de Kaa, M. P. Schoenberg, J. A. Witjes, and L. A. Kiemeney, “Clinical Epidemiology of Nonurothelial Bladder Cancer: Analysis of The Netherlands Cancer Registry,” J. Urol., vol. 183, no. 3, pp. 915–920, 2010, doi: 10.1016/j.juro.2009.11.018.
C. H. C. Kong et al., “Clinicopathological features of bladder tumours in a single institution in Malaysia,” Asian Pacific J. Cancer Prev., vol. 11, no. 1, pp. 149–152, 2010.
Sarah Ali Nehmaa, “Distribution of CNF1among Escherichia coli isolates from urinary tract infection and bladder cancer in southern of Iraq,” Univ. Thi-Qar J. Sci., vol. 10, no. 1(SI), pp. 190–193, 2023, doi: 10.32792/utq/utjsci/v10i1(si).1028.
A. C.C., B. A.A., A. F.B., D. A.O., A. O.R., and E. S.O., “Bladder cancer in Lagos: a 15 year histopathologic review,” Niger. Postgrad. Med. J., vol. 17, no. 1, pp. 40–44, 2010.
P. F. Rambau, P. L. Chalya, and K. Jackson, “Schistosomiasis and urinary bladder cancer in North Western Tanzania: A retrospective review of 185 patients,” Infect. Agent. Cancer, vol. 8, no. 1, pp. 19–24, 2013, doi: 10.1186/1750-9378-8-19.
R. L. Siegel, K. D. Miller, and A. Jemal, “Cancer statistics, 2019,” CA. Cancer J. Clin., vol. 69, no. 1, pp. 7–34, 2019, doi: 10.3322/caac.21551.
A. A. El-Siddig, A. M. Albasri, A. S. Hussainy, and A. S. Alhujaily, “Urinary bladder cancer in adults: A histopathological experience from Madinah, Saudi Arabia,” J. Pak. Med. Assoc., vol. 67, no. 1, pp. 83–86, 2017.
A. M. Al Khader, N. I. A. Shahin, F. N. Obeidat, and M. A. Al-Chalabi, “Urinary bladder cancer in Jordanian adults: A histopathological and epidemiological study from a tertiary care center in Amman,” J. Pak. Med. Assoc., vol. 69, no. 3, pp. 415–417, 2019.
M. S. Abbood, “The Role of Angiogenesis Factor in Bladder Tumors,” J.Thi-Qar Sci, vol. 5, no. 3, pp. 1–5, 2015.
P. Care, “Bladder cancer: diagnosis and management of bladder cancer: © NICE (2015) Bladder cancer: diagnosis and management of bladder cancer,” BJU Int., vol. 120, no. 6, pp. 755–765, 2017, doi: 10.1111/bju.14045.
Downloads
Published
License
Copyright (c) 2023 University of Thi-Qar Journal of Science
This work is licensed under a Creative Commons Attribution 4.0 International License.
