Assessment of Thyroid Hormones and Vitamin D Levels in Patients with Hereditary Hemoglobinopathies
Keywords:
Thyroid hormones,, Parathyroid hormone,, Vitamin D,, Hemoglobinopathies.Abstract
Background: Hemoglobinopathies are ultimately developed many complications with a high of morbidity, secondary to iron overload. Thyroid dysfunction and bone disorders are the most common clinical manifestations.
Methods: A case control study that included (140) patients with hemoglobinopathies and (50) healthy participants as a control. Anthropometric and biochemical measurements were estimated for all participants by standard methods.
Results: This study were shown no significant differences (p > 0.05) for vitamin D, calcium, parathyroid hormone (PTH), thyroid stimulating hormone (TSH), free triiodothyronine (FT3) and free thyroid hormone (FT4). On other hand, showed significant (p <0.05) increase levels of phosphorus and ferritin in patient
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