Syntheses, Characterization and biological Activity of a new ligand [4-[(1E)- ethylideneamino]-5-phenyl-4H-1,2,4-triazole-3-thiol with some transition metals complexes

Abstract

Anew Ligand 4-[(1E)-ethylideneamino]-5-phenyl-4H-1,2,4-triazole-3-thiole with its
(CrCl3.6H2O,FeCl3.6H2O,CoCl3,NiCl2.6H2OandCuCl2.6H2O)complexes were synthesized .The authenticity of
the ligand and its transition metal complexes were established by elemental analyses, conductance, as well as
spectroscopic (IR, 1HNMR, mass It may be concluded that the ligand coordinate through Nitrogen(N1) and
sulfer(S12) atoms as shown in figure (1). This view is further supported by the appearance of a band
corresponding to the metal–nitrogen stretching at 410–555 cm–1 in the complexes. the Ni and Cu atoms
leading to the formation tetrahedral geometry .Octahedral geometry was proposed for the(Cr(III),Fe(III) and
Co(III) prepared complex. Figure(2). All complexes and their parent organic moiety have been screened for
antibacterial (Table4) by using spread method and measurement inhibition zone by using (DMSO). this
studying showed positivity results. By appear lager inhibition zone against E-coli and staph aurens. Figure(3)